Methylfolate Plus by Biotics Research supplies folate, in the active form of (6S)-5-Methyltetrahydrofolic acid, glucosamine salt. Methylfolate is a highly absorbable, activated form of folate, which does not require enzymatic conversion to 5-methylfolate in the body. The glucosamine salt form utilized in Methylfolate Plus is more stable than other forms of methylfolate often used.